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André Charlett BSc MSc



Obtained First Class Hons. degree in Mathematics, and MSc in Medical Statistics and Information Technology, at University of Leicester. Graduate Member, Institute of Mathematics and its Applications; Fellow, Royal Statistical Society. Appointed MRC Scientist in Medical Statistics, Clinical Research Centre, Harrow. Worked in a team of statisticians with great diversity in expertise, advising and collaborating with basic and clinical scientists on design of experiments, analysis and presentation. Main coherent association was with Drs RJ Dobbs, SM Dobbs, Clive Weller of the Therapeutics Research Group: we developed a particular interest in use of statistical modelling to explore therapeutic/preventative interventions and generate hypothesis on causation of disease. Had mathematical role in design of computer software for objective assessments of features of parkinsonism. In 1993, appointed as a Principal Statistician at the Public Health Laboratory Service, London. In 2002, appointed Head of Statistics Unit of, what is now, the Health Protection Agency. Epidemiological work has focused on local and national surveillance, assessing and developing policies and practice in relation to hospital- and community-acquired infection, and evaluating laboratory procedures. This has provided insights, and developed my expertise, for the 'What’s Driving Parkinson’s programme' on parkinsonism, as Hon. Senior Lecturer at the Institute of Psychiatry. With core team have used statistical modeling to generate a coherent, hierarchical, biological-plausible hypothesis on the causation and propogation of idiopathic parkinsonism.